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Induction of redox changes, inducible nitric oxide synthase and cyclooxygenase-2 by chronic cadmium exposure in mouse peritoneal macrophages
(Elsevier Ireland, 2003-11-30)
Redox changes and the secretion of inflammatory mediators were investigated in resident peritoneal macrophages of mice chronically exposed to cadmium (Cd, 15 ppm for 2 months) through drinking water. Our results showed ...
Induction of nitric oxide synthase activity in adrenal cells
(Taylor & Francis, 2000-12)
The induction of nitric oxide synthase (NOS) II by bacterial lypopolysaccharide (LPS) was studied in a steroidogenic mouse tumor adrenal cell line (Y1). Conditioned media from LPS-stimulated peritoneal macrophages induced ...
Activation of nitric oxide synthase through muscarinic receptors in rat parotid gland
(Elsevier Science, 2002-08)
Muscarinic receptors play an important role in secretory and vasodilator responses in rat salivary glands. Nitric oxide synthase (NOS) activity was found coupled to muscarinic receptor activation as well as to nitric ...
Hypothyroidism: Age-related influence on cardiovascular nitric oxide system in rats
(W B Saunders Co-Elsevier Inc, 2012-09)
This study investigates whether changes in nitric oxide (NO) production participate in the cardiovascular manifestations of hypothyroidism and whether these changes are age-related. Sprague-Dawley rats aged 2 and 18 months ...
Role of endogenous nitric oxide in unilateral ureteropelvic junction obstruction in children
(Nature Publishing Group, 2003-12)
Background. Obstructive nephropathy leads to tubulointerstitial fibrosis and loss of renal function. Nitric oxide has been shown to have antifibrotic properties. We examined nitric oxide synthase (NOS) activity and expression ...
Alcohol hangover induces nitric oxide metabolism changes by impairing NMDA receptor-PSD95-nNOS pathway
(Academic Press Inc Elsevier Science, 2021-09)
Alcohol hangover is defined as the combination of mental and physical symptoms experienced the day after a single episode of heavy drinking, starting when blood alcohol concentration approaches zero. We previously evidenced ...
Ghrelin induced memory facilitation implicates nitric oxide synthase activation and decrease in the threshold to promote LTP in hippocampal dentate gyrus
(Pergamon-Elsevier Science Ltd, 2010-08)
Although the hypothalamus has been long considered the main ghrelin (Ghr) target organ mediating orexigenic effects, recently it has been shown that in-vivo Ghr hippocampus administration improves learning and memory in ...
Nitric oxide, complex I, and the modulation of mitochondrial reactive species in biology and disease
(Elsevier Science, 2004-02)
Mitochondria are the specialized organelles for energy metabolism but also participate in the production of O2 active species, cell cycle regulation, apoptosis and thermogenesis. Classically, regulation of mitochondrial ...
Nitric oxide synthases from photosynthetic organisms improve growth and confer nitrosative stress tolerance in E. coli. Insights on the pterin cofactor
(Academic Press Inc Elsevier Science, 2021-03)
Nitric oxide synthase (NOS) synthesizes NO from the substrate L-arginine (Arg). NOS with distinct biochemical properties were characterized from two photosynthetic microorganisms, the unicellular algae Ostreococcus tauri ...
Nitric oxide mediates the inhibitory effect of tumor necrosis factor-α on prolactin release
(Karger, 2001-12)
Tumor necrosis factor-α (TNF-α) is a pleiotropic cytokine that markedly affects neuroendocrine functions. This cytokine is expressed in the anterior pituitary where its receptors are also present. Nitric oxide (NO) is ...